Siah: New Players in the Cellular Response to Hypoxia
نویسندگان
چکیده
منابع مشابه
Siah Proteins, HIF Prolyl Hydroxylases, and the Physiological Response to Hypoxia
New evidence suggests that at least two members of the family of hypoxia-inducible factor (HIF) prolyl hydroxylases that regulate HIF stability in response to oxygen (O2) availability are also targeted for proteosome-dependent degradation by the E3 ubiquitin ligases Siah1a and Siah2. This preview examines cellular responses to O2 deprivation (hypoxia) and the complexity of the regulation of the...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2004
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.3.11.1207